MATERNAL HIGH-FAT DIET MODIFIES EPIGENETIC MARKS H3K27ME3 AND H3K27AC IN BONE TO REGULATE OFFSPRING OSTEOBLASTOGENESIS IN MICE

Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice

Studies from both humans and animal models indicated that maternal chronic poor-quality diet, especially a high fat diet (HFD), is significantly associated with reduced bone density and childhood fractures in offspring.When previously studied in a rat model, our data suggested that maternal HFD changes epigenetic marks such as DNA methylation and h

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Disseminated cutaneous rhinosporidiosis: Revisited

A vegetative growth in the nasal mucosa and nasopharynx present for a considerable period of time raises the possibility of rhinosporidiosis.Such presentation in the Indian subcontinent read more is not rare but erythematous cauliflower-like or tumor-like growths often reaching large size present on various areas of the skin without necessarily inv

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